Then the user closes and reopens Outlook. Modifying the Outlook profile by using the 'Profiles' registry path is not supported and may cause your Outlook profile to be in an unsupported state.Then I tried to delete my Outlook profile and set it up again.Opened outlook and selected the new 'outlook' mail profile generated in part by step 7. For me it seems that the source of the problem lies somewhere within the 'going online' process and/or connection with the (hosted exchange) server. Enable the below GPO to Prevent Indexing Microsoft Office Outlook. With Outlook, you get an e-mail, calendar, contacts, and much more all in a single app, yet Outlook still has its issues at times despite all that.Outlook unable to sign in to Office 365 email account after MFA Enabled.Sometimes Microsoft Outlook may stuck at loading screen due to faulty add-ins.A new wizard will appear on the screen, click “ More Setting ” to open the Microsoft Exchange dialog box, and then select the “ Security ” Tab. Look at the list of add-ins in the Active Application Add-ins section. Configuration of the enrollment profile for the Setup Assistant with modern authentication. Read more: Install second Exchange Server in domain » Final thoughts. Confirmed outlook re-downloaded mail data and profile persisted though reboots. Fix Outlook hanging on Loading Profile.I was able to connect outlook to Office365 on another computer and so knew the MFA was working.Press the Enter key to start Outlook in protected mode.Outlook stuck on loading profile after mfa

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